In your input control that has typeahead attached to it & if you also have a picker associated with it, you can add a pickervalidator.
<xp:this.validators>
<xe:pickerValidator for="namePicker1"
message="The value is invalid">
</xe:pickerValidator>
</xp:this.validators>
which (in my testing) will get triggered when you submit the page.
Take a look at the Domino_Pickers.xsp in the XPages Extension Library Demo Db available on OpenNTF: http://www.openntf.org/internal/home.nsf/project.xsp?action=openDocument&name=XPages%20Extension%20Library